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Kober, L.O.M. ; Ellwart, J.W. ; Brettle, H.

Effect of the Pulse Length of Ultrasound on Cell Membrane Damage in Vitro.

J. Acoust. Soc. Am. 86, 6-7 (1989)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Suspended cells of a human lymphoblastic cell line were exposed to pulsed ultrasound of 775 kHz. The pulse lengths were varied between 16 and 1000 microseconds. The mark/space ratio was always kept at 1:1. Two ultrasound intensity levels were used: 3.6 and 6.4 W/cm2 spatial peak and temporal peak. After an exposure time of 5 min, cell membrane damage was measured cytometrically by a dye exclusion test. No membrane damage was observable at 16 microseconds, whereas, at pulse lengths of 1000 microseconds, about one-third of the cells were damaged.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0001-4966
e-ISSN 1520-8524
Zeitschrift Journal of the Acoustical Society of America
Quellenangaben Band: 86, Heft: 1, Seiten: 6-7 Artikelnummer: , Supplement: ,
Verlag American Institute of Physics (AIP)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Clinical Molecular Biology and Tumor Genetics (K.MOLBI)