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The Effect of Fetal Irradiation on the Growth of Postnatally Xenotransplanted Tumour Cells.

Int. J. Radiat. Biol. 55, 821-827 (1989)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Exposure of the mouse fetus (NMRI-strain) to 1.0 Gy X-irradiation has a marked effect on postnatally xenotransplanted glioma cells. In comparison to non-irradiated animals, irradiation on gestation day 14 resulted in: (a) a significantly higher rate of animals which failed to develop visible tumours growing from the inoculum; (b) a significant inhibition of the growth rate of solid gliomas; (c) a pronounced granulocytic and mast cell infiltration, and tissue necrosis, in the invading gliomas. The results suggest that irradiation in prenatal life exerts an amplifying effect on the antitumour response in postnatal life.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Quellenangaben Band: 55, Heft: , Seiten: 821-827 Artikelnummer: , Supplement: ,
Verlag Informa Healthcare
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed