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Bors, W. ; Michel, C. ; Saran, M.

Flavonoid Antioxidants: Rate Constants for Reactions with Oxygen Radicals.

Methods Enzymol. 234, 420-429 (1994)
DOI
This chapter describes the flavonoids that are plant secondary metabolites having a polyphenol structure, occurring mostly as glycosides or methoxylated derivatives, and sometimes as aglycones. It has been assumed for years that they act as antioxidants, primarily based on the fact that they extend the shelf-life of fat-containing foodstuffs. In contrast, an antioxidative function in plants themselves is still a matter of debate, even though protective effects during plant photooxidative processes. The biochemical background for the antioxidative effect of flavonoids is inhibition of lipid peroxidation, which has been observed on numerous occasions. Owing to the polyphenol structure, this inhibition can be brought about either by chelating of transition metals or by scavenging of free radicals with the formation of less reactive flavonoid aroxyl radicals. At present, radical scavenging is clearly the favored mechanism as evidenced by the lopsided ratio of reports on scavenging versus chelating properties of flavonoids. The chapter discusses the methods for oxygen radical generation. Radiolytic, photolytic, chemical, and enzymatic systems may be used as sources of oxygen radicals.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0076-6879
e-ISSN 0076-6879
Konferenztitel Oxygen Radicals in Biological Systems Part D
Zeitschrift Methods in Enzymology
Quellenangaben Band: 234, Heft: , Seiten: 420-429 Artikelnummer: , Supplement: ,
Verlag Elsevier
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Biology (ISB)