PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Harper, R.A. ; Stirling, C. ; Townsend, K.M.S. ; Kreyling, W.G. ; Patrick, G.

Intracellular Particle Dissolution in Macrophages Isolated from the Lung of the Fischer(F-344) Rat.

Exp. Lung Res. 20, 143-156 (1994)
Verlagsversion DOI PMC
Open Access Gold
Alveolar macrophages were removed from male F-344 rats by bronchoalveolar lavage and maintained in vitro for 14 days. Over this period the macrophages remained viable as judged by propidium iodide exclusion, lysosomal uptake of acridine orange, and phagocytosis of 1.75-microns latex beads. After 7 and 14 days of culture the cells contained lipid droplets. The macrophages were shown to ingest and dissolve monodisperse 57Co3O4 particles, which were relatively insoluble in extracellular medium. The fraction of 57Co3O4 dissolved intracellularly was determined at intervals during the culture period. The mean dissolution rate (+/- SEM) was 0.36 +/- 0.02% per day for the F-344 rat. This was lower than 1.4 +/- 0.05% per day estimated by Kreyling in macrophages from the beagle dog. The significance of this difference is discussed.
Impact Factor
Scopus SNIP
Scopus
Cited By
Altmetric
0.000
0.000
7
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Sprache englisch
Veröffentlichungsjahr 1994
HGF-Berichtsjahr 0
ISSN (print) / ISBN 0190-2148
e-ISSN 1521-0499
Zeitschrift Experimental Lung Research
Quellenangaben Band: 20, Heft: 2, Seiten: 143-156 Artikelnummer: , Supplement: ,
Verlag Informa Healthcare
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Protection (ISS)
PubMed ID 8020429
DOI 10.3109/01902149409064379
Erfassungsdatum 1994-12-31
[➜Korrektur melden]