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Intratumoral alterations of dendritic-cell differentiation and CD8+ T-cell energy are immune escape mechanisms of clear cell renal cell carcinoma.
OncoImmunology 1, 1451-1453 (2012)
Cytotoxic lymphocytes and dendritic cells infiltrating human renal cell carcinoma (RCC) are not sufficient to prevent tumor progression. Our studies identified alterations of the immune cell infiltrate as well as some of the underlying mechanisms. This knowledge should facilitate the development of anti-RCC therapies that achieve better tumor control.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Sonstiges: Meinungsartikel
Schlagwörter
Dendritic Cells ; Immune Escape ; Renal Cell Carcinoma ; Tumor-infiltrating Lymphocytes ; Tumor Milieu
ISSN (print) / ISBN
2162-4011
e-ISSN
2162-402X
Zeitschrift
OncoImmunology
Quellenangaben
Band: 1,
Heft: 8,
Seiten: 1451-1453
Verlag
Taylor & Francis
Verlagsort
Philadelphia
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Molecular Immunology (IMI)