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Blood collection from mice and hematological analyses on mouse blood.
Curr. Protoc. Mouse Biol. 3, 101-119 (2013)
Basic phenotyping of inbred mouse strains and genetically modified mouse models usually includes the determination of blood-based parameters as a diagnostic screen for genotype effects on metabolism and organ function. A broad range of analytes, including hematological parameters, can be reliably determined in mouse blood, if appropriate samples are available. Here we describe recommended techniques for blood collection from mice and the considerations that have to be taken into account to get adequate samples for hematological investigations. Furthermore, we describe established methods used in the German Mouse Clinic (GMC) to determine hematological parameters in the mouse.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
mouse; blood sample collection; hematology
Sprache
englisch
Veröffentlichungsjahr
2013
HGF-Berichtsjahr
0
ISSN (print) / ISBN
2161-2617
Zeitschrift
Current Protocols of Mouse Biology
Quellenangaben
Band: 3,
Seiten: 101-119
Verlag
Wiley
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Experimental Genetics (IEG)
POF Topic(s)
30201 - Metabolic Health
90000 - German Center for Diabetes Research
90000 - German Center for Diabetes Research
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-500600-003
G-500600-001
G-501900-063
G-500600-001
G-501900-063
Erfassungsdatum
2013-07-03