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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Small molecule screening at Helmholtz Zentrum München - from biology to molecules.
Comb. Chem. High Throughput Screen. 7, 266-271 (2014)
Within the last few years the Helmholtz Zentrum München has established several initiatives enabling the translation of basic research results into discovery of novel small molecules that affect pathomechanisms of chronic and complex diseases. Here, one of the main operations is the Assay Development and Screening Platform (ADSP) that has state-of-the-art equipment for compound screening and provides knowledge in a variety of biochemical or cell-based phenotypic assays. In particular, ADSP has a strong focus on complex assays such as high-content screening in stem cells that are likely to provide an innovative approach complementary to biochemical assays for the discovery of novel small molecules modulating key biological processes.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Academic Screening ; Assay Development ; Drug Discovery ; High Content Screening ; Hts ; Liquid Handling ; Phenotypic Screening
ISSN (print) / ISBN
1386-2073
e-ISSN
1875-5402
Quellenangaben
Band: 7,
Heft: 3,
Seiten: 266-271
Verlag
Bentham Science Publishers
Verlagsort
Sharjah
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed