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Schorpp, K.K. ; Hadian, K.

Small molecule screening at Helmholtz Zentrum München - from biology to molecules.

Comb. Chem. High Throughput Screen. 7, 266-271 (2014)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Within the last few years the Helmholtz Zentrum München has established several initiatives enabling the translation of basic research results into discovery of novel small molecules that affect pathomechanisms of chronic and complex diseases. Here, one of the main operations is the Assay Development and Screening Platform (ADSP) that has state-of-the-art equipment for compound screening and provides knowledge in a variety of biochemical or cell-based phenotypic assays. In particular, ADSP has a strong focus on complex assays such as high-content screening in stem cells that are likely to provide an innovative approach complementary to biochemical assays for the discovery of novel small molecules modulating key biological processes.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Academic Screening ; Assay Development ; Drug Discovery ; High Content Screening ; Hts ; Liquid Handling ; Phenotypic Screening
Sprache englisch
Veröffentlichungsjahr 2014
HGF-Berichtsjahr 2014
ISSN (print) / ISBN 1386-2073
e-ISSN 1875-5402
Zeitschrift Combinatorial Chemistry & High Throughput Screening
Quellenangaben Band: 7, Heft: 3, Seiten: 266-271 Artikelnummer: , Supplement: ,
Verlag Bentham Science Publishers
Verlagsort Sharjah
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Molecular Toxicology and Pharmacology (TOX)
POF Topic(s) 30203 - Molecular Targets and Therapies
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-505293-001
PubMed ID 24409952
DOI 10.2174/1386207317666140109124410
WOS ID WOS:000333188300009
Scopus ID 84897980481
Erfassungsdatum 2014-02-04
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