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Schwartz, M.W.* ; Tschöp, M.H. ; Zeltser, L.M.*

A mother's influence on metabolic disorders.

J. Nat. Med. 20, 244-245 (2014)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Human epidemiological studies have revealed that maternal obesity predisposes offspring to metabolic disorders, though little is known about the mechanism that causes this phenomenon. In a step forward, Vogt et al. have shown in mice that the offspring of mothers fed a high-fat diet during lactation show an alteration in the number of projections in nerves in the hypothalamus in the brain and in the pancreas. These offspring are predisposed to be obese and develop diabetes, and the mechanism by which these connections are altered seems to be through insulin signaling. Here we asked three experts what the implications of these findings might be to humans.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Editorial
Korrespondenzautor
Schlagwörter Hypothalamic Neurons; Leptin; Circuits; Diet
ISSN (print) / ISBN 1340-3443
e-ISSN 1861-0293
Zeitschrift Journal of natural medicines
Quellenangaben Band: 20, Heft: 3, Seiten: 244-245 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Tokyo [u.a.]
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes and Obesity (IDO)