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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
New pharmacological strategies to fight enveloped viruses.
Trends Pharmacol. Sci. 35, 470-478 (2014)
Enveloped viruses pose an important health threat because most of the persistent and many emerging viruses are enveloped. In particular, newly emerging viruses create a need to develop broad-spectrum antivirals, which usually are obtained by targeting host cell factors. Persistent viruses have developed efficient strategies to escape host immune control, and treatment options are limited. Targeting host cell factors essential for virus persistence, or immune-based therapies provide alternative approaches. In this review, we therefore focus on recent developments to generate antivirals targeting host cell factors or immune-based therapeutic approaches to fight infections with enveloped viruses.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Antiviral Agents ; Emerging Disease ; Host Cell Factors ; Immunotherapy; Human-immunodeficiency-virus; Hepatitis-b; Monoclonal-antibodies; Human Cytomegalovirus; Hcv Infection; Cells; Inhibitors; Entry; Diseases; Receptor
ISSN (print) / ISBN
0165-6147
e-ISSN
1873-3735
Zeitschrift
Trends in Pharmacological Sciences
Quellenangaben
Band: 35,
Heft: 9,
Seiten: 470-478
Verlag
Cell Press
Verlagsort
Amsterdam
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed