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Chronic radiation damage in the rectum of the rat after protracted fractionated irradiation.

Radiother. Oncol. 7, 155-163 (1986)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
In this experiment, a protracted fractionation regime (18 fractions/170 days, dose/fraction: 6,7,8 Gy) caused late rectal obstruction in rats independently of any clinically detectable acute damage. Rectal obstruction was due to an ulcer which developed secondary to an atrophic mucosa and capillary damage. In agreement with our earlier protracted fractionation schedules, the results were not fitted well by the linear-quadratic model. However, there are indications of relatively low alpha/beta values. Hydronephroses and hydroureters were the only competing risks to rectal obstruction and they occurred independently of it.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0167-8140
e-ISSN 1879-0887
Quellenangaben Band: 7, Heft: 2, Seiten: 155-163 Artikelnummer: , Supplement: ,
Verlag Elsevier
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Abteilung für Strahlenbiologie und Biophysik