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Ianka, G.E.* ; Lau, B. ; Haas, R.J.* ; von Lieven, H.P.* ; Lampert, F.H.*

Combination chemotherapy and radiotherapy for Hodgkin's disease in children.

Eur. J. Pediatr. 127, 287-292 (1978)

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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.

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31 children with Hodgkin's disease were treated at the Children's Hospital, University of Munich, between 1963-1976. Before 1971 the diagnosis of abdominal involvement was based solely on physical findings and radiological studies. Treatment consisted of involved-field radiation; chemotherapy was added in selected cases. Of 15 children treated between 1963-1971 5 are still in their first remission and 2 in their second remission. Since 1971 exploratory laparotomy and splenectomy have been performed. Radiation therapy was changed from involved-to extended-field therapy and combination chemotherapy was added in all the children. No patient from this group of 16 children relapsed during a median observation time of 24 months (range 12-55 months). The toxicity of the combined treatment does not seem to be prohibitive.

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