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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Attachment of human chromatin fibers to the nuclear membrane, as seen by electron microscopy.
Hum. Genet. 13, 285-295 (1971)
Whole-mount preparations and thin sections of human interphase cells and metaphase chromosomes were examined by electron microscopy. Irregularly folded, 250 Å thick fibers, which is the basic substructure of inactive chromatin and mitotic chromosomes, were found to be firmly attached to the annuli of the inner nuclear membrane. At metaphase, fragments of the nuclear membrane were seen to adhere to the chromatids. Single fibers stretching out from the telomeres were observed connecting chromatids of nonhomologous chromosomes. A possible model of DNA replication at the nuclear pore complex is presented.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0340-6717
e-ISSN
1432-1203
Zeitschrift
Human Genetics
Quellenangaben
Band: 13,
Heft: 4,
Seiten: 285-295
Verlag
Springer
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Hämatologie