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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The influence of oxygen on the survival and yield of DNA double-Strand breaks in irradiated yeast cells.
Int. J. Radiat. Biol. 36, 261-270 (1979)
Survival and induction of DNA double-strand breaks were studied in cells of Saccharomyces cerevisiae irradiated under oxic or anoxic conditions with 30 MeV electrons. A linear relationship between DNA double-strand breakage and dose was found in both cases. The o.e.r.-value for colony forming ability was found to be 1·9 ± 0·2, whereas the o.e.r.-value for DNA double-strand breakage was 3·0 ± 0·1. These results are not inconsistent with the idea that DNA double-strand breaks are involved in killing of yeast cells. The frequency of induction of DNA double-strand breaks was found to be 0·74 × 10-11 double-strand breaks per g/mol per Gy when cells were irradiated under oxygen and 0·24 × 10-11 double-strand breaks per g/mol per Gy under nitrogen.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Zeitschrift
International Journal of Radiation Biology
Quellenangaben
Band: 36,
Heft: 3,
Seiten: 261-270
Verlag
Informa Healthcare
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Biologie