Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Simulation of genetic networks modelled by piecewise deterministic Markov processes.
IET Syst. Biol. 2, 113-135 (2008)
The authors propose piecewise deterministic Markov processes as an alternative approach to model gene regulatory networks. A hybrid simulation algorithm is presented and discussed, and several standard regulatory modules are analysed by numerical means. It is shown that despite of the partial simplification of the mesoscopic nature of regulatory networks such processes are suitable to reveal the intrinsic noise effects because of the low copy numbers of genes.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
1751-8849
e-ISSN
1751-8857
Zeitschrift
IET Systems Biology
Quellenangaben
Band: 2,
Heft: 3,
Seiten: 113-135
Verlag
Institution of Engineering and Technology (IET)
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Biomathematics and Biometry (IBB)