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Toxicity tests with luminescent photobacteria and quantitative structure activity relationships for nitroparaffins.
Chemosphere 24, 1835-1843 (1992)
EC50 values of different nitroparaffins were determined by a photobacterium phosphoreum toxicity test. Octanol/water partition coefficients were determined by a reversed phase HPLC method. From these experimental data quantitative structure activity relationships were deduced which point to a dependence of toxicity on a 'form factor' that includes the number of methyl and methylene groups in a molecule. The hypothesis will be formulated that the specific effects depend on the number of methylgroups and an equation for specific effects is given
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0045-6535
e-ISSN
1879-1298
Zeitschrift
Chemosphere
Quellenangaben
Band: 24,
Heft: 12,
Seiten: 1835-1843
Verlag
Elsevier
Verlagsort
Kidlington, Oxford
Begutachtungsstatus
Peer reviewed
Institut(e)
PPM-MEX-Molecular EXposomics (MEX)
Institute of Ecological Chemistry (IOEC)
Institute of Ecological Chemistry (IOEC)