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Frankenberg-Schwager, M. ; Frankenberg, D. ; Bloecher, D. ; Adamczyk, C.

Repair of DNA double-strand breaks in irradiated yeast cells under nongrowth conditions.

Radiat. Res. 82, 498-510 (1980)
Verlagsversion DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
We show that in diploid yeast radiation-induced DNA double-strand breaks can be repaired under nongrowth conditions at 30°C and that liquid holding recovery of colony-forming ability is accompanied by a decrease in the number of double-strand breaks per cell. The kinetics of double-strand break repair under nongrowth conditions depend on the dose applied. For the highest dose used (2400 Gy) repair is completed within about 48 hr. We have verified that double-strand breaks which remain unrepaired after 48 hr are irreparable under nongrowth conditions. The linear relationship between the initial number of double-strand breaks and dose is converted into a quadratic function of irreparable double-strand breaks with and dose during liquid holding treatment of cells.
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Publikationstyp Sonstiges: Korrektur, Ergänzung
Korrespondenzautor
ISSN (print) / ISBN 0033-7587
e-ISSN 1938-5404
Zeitschrift Radiation Research
Quellenangaben Band: 82, Heft: 3, Seiten: 498-510 Artikelnummer: , Supplement: ,
Verlag Radiation Research Society
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Abteilung Biophysikalische Strahlenforschung