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Regulation of late functions in Salmonella bateriophages P22 and L studied by assaying endolysin synthesis.

J. Virol. 32, 1-7 (1979)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The rate of endolysin synthesis in Salmonella typhimurium cells infected by bacteriophage P22 or L was taken as a measure for the activity of 23 gene product (the positive regulator for the 'late' genes of P22 and L). Endolysin is coded for by gene 19. The amber mutations in gene 23 of P22 and L, used in this study, reduced the rate of endolysin synthesis by a factor of ca. 90 or P22 and of ca. 20 for L. In mixed infections with 19- and 23- mutants the 23 gene products of P22 and L act as positive regulators for the respective gene 19 in cis and in trans. Cross-specificity of the 23 gene products, i.e. turning on expression of gene 19 on a chromosome of the other species, could not be demonstrated.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0022-538X
e-ISSN 1098-5514
Zeitschrift Journal of Virology
Quellenangaben Band: 32, Heft: 1, Seiten: 1-7 Artikelnummer: , Supplement: ,
Verlag American Society for Microbiology (ASM)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institut für Mikrobiologie