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Long-term exposure of dogs to a sulphite aerosol: III. Effect of lung clearance.
J. Aerosol Sci. 21, S479-S482 (1990)
Eight dogs were exposed to a sodium bisulphite aerosol during 290 days. Lung clearance was tested with moderately soluble and insoluble aerosol particles after a single inhalation. Three dogs showed significant changes in clearance rate of moderately soluble particles during the sulphite exposure compared to the clearance rate during clean air exposure. The results were confirmed by in vitro clearance measurements in alveolar macrophages.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Chronio Exposure ; Clearance Mechanism ; Dog ; Lung ; Lung Retention ; Mechanical Particle Transport, Translocation, Intracellular Particle Dissolution ; Sulphite Aerosol
ISSN (print) / ISBN
0021-8502
e-ISSN
1879-1964
Zeitschrift
Journal of Aerosol Science
Quellenangaben
Band: 21,
Heft: SUPPL. 1,
Seiten: S479-S482
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Radiation Protection (ISS)