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Genetische Wirkungen kleiner Stahlen-Dosen.
Genetic effect of low doses of lonizing radiation.
Naturwissenschaften 74, 3-11 (1987)
There are several approaches to evaluate the genetic effects of low doses of ionizing radiation in a human population. Based on experiments on mice using high doses, the genetic risk for humans has to be derived by extrapolation to low doses, assuming mouse and man respond in a similar way. Microdosimetric considerations indicate a linear relationship; studies on the molecular mechanism of radiation-induced mutagenesis lead to the conclusion that, in addition to a constitutive mutagenic process, an inducible compound exists which may cause linear-quadratic dose-effect curves. Linear extrapolation seems thus to be justified; however, the genetic risk of low doses may be slightly overestimated.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0028-1042
e-ISSN
1432-1904
Zeitschrift
Naturwissenschaften, Die
Quellenangaben
Band: 74,
Heft: 1,
Seiten: 3-11
Verlag
Springer
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Radiation Biology (ISB)