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Herbert, A.* ; Gerry, N.P.* ; McQueen, M.B.* ; Heid, I.M. ; Pfeufer, A. ; Illig, T. ; Wichmann, H.-E. ; Meitinger, T. ; Hunter, D.* ; Hu, F.B.* ; Colditz, G.* ; Hinney, A.* ; Hebebrand, J.* ; Koberwitz, K. ; Zhu, X.F.* ; Cooper, R.* ; Ardlie, K.* ; Lyon, H.* ; Hirschhorn, J.N.* ; Laird, N.M.* ; Lenburg, M.E.* ; Lange, C.* ; Christman, M.F.*

Response to Comments on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity".

Science 315, 187e (2007)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Identification of genetic variants affecting complex traits such as obesity is confounded by many types of bias, especially when effect sizes are small. Given our findings of a positive association between rs7566605 and body mass index in four out of five separate samples, a false positive finding cannot be ruled out with certainty but seems unlikely. Meta-analyses of multiple large studies will help refine the estimate of the effects of rs7566605 on body mass index.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0036-8075
e-ISSN 1095-9203
Zeitschrift Science
Quellenangaben Band: 315, Heft: 5809, Seiten: 187e Artikelnummer: , Supplement: ,
Verlag American Association for the Advancement of Science (AAAS)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)