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Mechanisms of aerosol particle deposition.
Chest 80, 820-823 (1981)
An aerosol with particles aerodynamically larger than 0.5 μm inspired through the nose is partially filtered in the nasal passages by inertial transport. Mouth-inspiration aerosols in the aerodynamic size range between 0.5 and 2 μm penetrate without particle losses to the alveolar region where they are partially filtered by gravitational sedimentation. Aerosols with larger particles inspired through the mouth experience partial collection by inertial impaction in the extrathoracic airways and by gravitational sedimentation and inertial impaction in the bronchial airways before effective filtration in the alveolated air-spaces due to gravitational sedimentation. Particles larger than 12 μm cannot penetrate to the alveolar region. With mouth-breathing particles more readily escape deposition in the extrathoracic and bronchial airways during expiration than during inspiration. Present knowledge tells us neither the smallest particle effectively transported by gravitational sedimentation in the respiratory tract nor the effectiveness there of diffusional transport.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0012-3692
e-ISSN
1931-3543
Zeitschrift
Chest
Quellenangaben
Band: 80,
Heft: 6 Suppl.,
Seiten: 820-823
Verlag
American College of Chest Physicians
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed