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Variation of mutation and recombination frequencies over a range of thymidylate concentrations in a diploid thymidylate auxotroph.
Curr. Genet. 7, 399-402 (1983)
A diploid yeast thymidylate auxotroph was grown under conditions of thymidylate stress ranging from depletion to excess levels of the nucleotide. High concentrations of thymidylate were mutagenic and recombinagenic whereas starvation for thymine nucleotides was recombinagenic and only slightly mutagenic. These results are discussed in relation to possible mutagenic and recombinagenic mechanisms of nucleotide pool imbalances.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0172-8083
e-ISSN
1432-0983
Zeitschrift
Current Genetics
Quellenangaben
Band: 7,
Heft: 5,
Seiten: 399-402
Verlag
Springer
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Abteilung für Strahlenbiologie und Biophysik