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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Acute lymphoblastic leukaemia cells in the diffusion chamber: Change of surface phenotype during the culture period.
Br. J. Haematol. 52, 319-325 (1982)
Peripheral blast cells from patients with acute lymphoblastic leukaemia were cultured in the diffusion chamber system. On different harvesting days the cALL antigen, surface immunoglobulin and T-cell antigen were investigated by direct immunofluorescence. Each cell type investigated showed a different response throughout culture, the commonest change observed being development into the B-cell axis. Our data demonstrate that the differentiation stop of a leukaemic cell can be overcome by using the diffusion chamber system. The data therefore give some insight into the stage of developmental arrest in acute lymphoblastic leukaemia.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0007-1048
e-ISSN
1365-2141
Zeitschrift
British Journal of Haematology
Quellenangaben
Band: 52,
Heft: 2,
Seiten: 319-325
Verlag
Wiley
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed