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Radiation induced heart disease in hypertensive rats.
Int. J. Radiat. Oncol. Biol. Phys. 14, 109-114 (1988)
Spontaneously hypertensive Wistar rats were given single doses of X rays to their heart. Irradiation decreased the blood pressure before any myocardial radiation damage was apparent. Male rats, which were more hypertensive than female rats, had a shorter survival time after local heart irradiation than female rats. Antihypertensive treatment with hydralazine did not increase the survival time. It is considered that myocardial hypertrophy is the cause of the increased susceptibility of spontaneously hypertensive rats to local heart irradiation.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Radiation-induced heart disease; Hypertension
ISSN (print) / ISBN
0360-3016
e-ISSN
0360-3016
Quellenangaben
Band: 14,
Heft: 1,
Seiten: 109-114
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Abteilung für Strahlenbiologie und Biophysik