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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Macrophage colony-stimulating activity is produced by three different EBV-transformed lymphoblastoid cell lines.
Cell. Immunol. 109, 246-254 (1987)
The lymphoblastoid cell lines BLY 9.84, Gl, and Pl constitutively release a colony-stimulating activity (CSA) which specifically stimulates murine macrophage progenitor cells in vitro. The biochemical characterization of BLY 9.84-derived CSA exhibits a molecular size of apparently 150-200 kDa even under dissociating conditions with 6 M guanidine hydrochloride or inhibition of glycosylation. Production of this CSA is inhibited by cycloheximide and its activity is destroyed by reduction with dithiothreitol. Replating experiments give evidence for a functional similarity with CSF-1 (macrophage colony-stimulating factor).
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0008-8749
e-ISSN
0008-8749
Zeitschrift
Cellular Immunology
Quellenangaben
Band: 109,
Heft: 1,
Seiten: 246-254
Verlag
Elsevier
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Experimentelle Hämatologie