Hygroscopic aerosol particles will grow during respiration depending on their own properties and the local relative humidity (RH). Lung deposition models are used to approximate the local deposition of NaCl aerosol particles for different humidity distributions in the upper human airways. A method has been described by G. A. Ferron et al. , which enables the determination of the local temperature, water vapor concentration and RH of the air in the nasopharynx and upper human airways. The mean RH over an airway cross-section shows a fast increase in the nasal region. It reaches a maximum value of 0. 997 in the trachea. A maximum in the particle size is found caused by the maximum in the RH. Such a maximum is not found for larger particle sizes. Since dry NaCl aerosol particles will not grow at RH less than approximately 0. 75, there is no growth in the nostrils. A delay in growth of 0. 01 sec is found. Three lung deposition models are used in the study reported, and one model is then reapplied to determine the local and total deposition probability of a single NaCl particle during the respiration circle. Refs.