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Haina, D. ; Landthaler, M.

Fundamentals of laser light interaction with human tissue, especially in the cardiovascular system.

Thorac. Cardiovasc. Surg. 36, 118-125 (1988)
DOI
The absorption of single photons in the molecules of biological tissue can induce various reactions. For the most medical laser applications the transformation from radiation energy into heat is relevant. The laser beam is used for coagulation or vaporization of tissue. The changes in tissue, which are created by light of different wavelengths depends on the thermal and optical properties (absorption and scatting) of tissue but also on the parameters of irradiation. As an example measurements from human skin are discussed. In the cardiovascular system laser light must have a clearly defined effect. Atherosclerotic plaques of different consistence have to be vaporized without damage of the vessel walls. From different reasons the usual medical CW-lasers, Argon-laser, CO2-laser and Nd:YAG-laser, are not optimal for direct ablation of arterial occlusions. In order to minimize reocclusion the walls of the channels have to be completely smooth and free of coagulation necrosis. This can be obtained by short laser pulses.Selection of a light wavelength, which is stronger absorbed in atherosclerotic plaques than in vessel walls and additional selective staining are two ways to reduce the risk of damaging the vessel walls.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Human tissue; Thermal properties; Optical properties; Coagulation; Vaporization; CW laser; Pulse laser; Angioplasty; Plaques; Blood vessels walls; Hot tip
ISSN (print) / ISBN 0040-6384
e-ISSN 1439-1902
Zeitschrift Thoracic and Cardiovascular Surgeon, The
Quellenangaben Band: 36, Heft: , Seiten: 118-125 Artikelnummer: , Supplement: ,
Verlag Thieme
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institut für angewandte Optik