Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Dose-dependent emergence of preneoplastic foci in rat livers after exposure to 2-nitropropane.
Arch. Toxicol. 64, 329-331 (1990)
Male and female Sprague-Dawley rats, 4-6 days old were exposed for 3 weeks (6 h/day, 5 days/week) to 2-nitropropane vapours of 0, 25, 40, 50, 80 and 125 ppm. One week later polychlorinated biphenyls (Clophen A50, 10 mg/kg body weight) were administered for promotion twice a week for 8 weeks. Thirteen weeks after starting the experiments the logarithms of the numbers of preneoplastic liver foci deficient in adenosine-5′-triphosphatase were found to be linearly related to the exposure concentrations of 2-nitropropane. Male rats exhibited an approximately four times lower foci incidence than females.
Impact Factor
Scopus SNIP
Scopus
Cited By
Cited By
Altmetric
0.000
0.000
3
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
2-nitropropane ; Inhalation ; Preneoplastic Liver Foci ; Rats
Sprache
englisch
Veröffentlichungsjahr
1990
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0340-5761
e-ISSN
1432-0738
Zeitschrift
Archives of Toxicology
Quellenangaben
Band: 64,
Heft: 4,
Seiten: 329-331
Verlag
Springer
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Toxikologie
Scopus ID
0025350433
Erfassungsdatum
1990-12-31