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Pyruvate and related α-ketoacids protect mammalian cells in culture against hydrogen peroxide-induced cytotoxicity.

Toxicol. Lett. 28, 93-98 (1985)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Pyruvate efficiently protected V79 Chinese hamster cells against the lethal effects of hydrogen peroxide. Protection was also provided by other α-ketoacids, such as α-ketobutyrate, α-ketoglutarate and α-ketoadipate, although higher concentrations were required. The corresponding β-ketoacids had no effect. The results indicate that pyruvate and other α-ketoacids possess antioxidant activity in vitro and, probably, in vivo.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0378-4274
e-ISSN 1879-3169
Zeitschrift Toxicology Letters
Quellenangaben Band: 28, Heft: 2-3, Seiten: 93-98 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort Amsterdam
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institut für Toxikologie und Biochemie