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Chromosome aberrations in human lymphocytes induced by fission neutrons.
Int. J. Radiat. Biol. 45, 449-457 (1984)
The dose-response relationships of dicentrics and excess acentrics were analysed after exposure of human lymphocytes to a mixed fission neutron-γray beam. From the analysis of exclusively first division cells a linear-quadratic relation was obtained for dicentrics with the ratio of linear and quadratic components, ζ equal to 2·76 Gy. Over the range of doses studied (0·04-1·97 Gy) intratrack events therefore predominated. This also applied to acentrics which were linearly related to dose. At the lowest level of observed effect and dose, r.b.e. values with respect to 60Co γrays of up to about 11 were derived for dicentrics and acentrics. With increasing neutron dose the r.b.e. decreased.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Chromosome Damge ; Dose-response Relationship ; Fission Neutrons ; Human Lymphocytes
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Zeitschrift
International Journal of Radiation Biology
Quellenangaben
Band: 45,
Heft: 5,
Seiten: 449-457
Verlag
Informa Healthcare
Begutachtungsstatus
Peer reviewed
Institut(e)
Abteilung für Strahlenbiologie und Biophysik