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Experimentelle Erfahrungen mit inraartikularen Injektionen des Alpha emittierenden Radionuklids 224Ra (ThX) in das Kniegelenk von Ratten.
Experimental experiences with intra-articular injections of the α-emitting radionuclide 224Ra (ThX) into the knee joint of a rat.
Z. Orthop. Unfallchir. 116, 234-239 (1978)
224Ra is used within the therapy of rheumatoid arthritis. The distribution of this radionuclide in the organism was investigated up to 7 days after incorporation in order to estimate a possible risk of late effects. In the autoradiographs we found strong blackenings at those bone surfaces which faced the injected knee-joint hole. In addition the radionuclide was deposited in skeletal growth-zones similarly as after i.v. and i.p. injections. The dosimetric data (particularly of knee-joint and skeleton) were calculated and compared with those which occur after the therapy of ankylosing spondylitis using i.v. 224Ra injections.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
1864-6697
e-ISSN
1438-941X
Zeitschrift
Zeitschrift für Orthopädie und Unfallchirurgie
Quellenangaben
Band: 116,
Heft: 2,
Seiten: 234-239
Verlag
Thieme
Verlagsort
Stuttgart ; New York, NY
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed