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Müller, W.A.

Studies on short-lived internal αemitters in mice and rats: Part II. 227th.

Int. J. Radiat. Biol. 20, 233-243 (1971)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
227Th is an interesting model for a short-lived bone 'surface-seeker' with αemission. The distribution after intraperitoneal injection of 227Th-citrate in the different organs is described. About 70 per cent of the injected Th was retained in the skeleton. The total dose burden depends to a high degree on distribution of decay products, especially 223Ra. Calculations were done for the skeletal dose burden in mice. They yielded 200 rads per 1 μCi of 227Th injected. The highest skeletal dose-rate (7 rads/day per 1 μCi/kg) was reached at the third day after injection. The possibility of bone sarcoma induction is discussed by comparison with dose relationships after incorporation of 228Th. A provisional mechanical technique is described for estimation - to a certain extent - of the activity at bone surface and volume separately.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Zeitschrift International Journal of Radiation Biology
Quellenangaben Band: 20, Heft: 3, Seiten: 233-243 Artikelnummer: , Supplement: ,
Verlag Informa Healthcare
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institut für Biologie