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Clonogenicity of the progeny of surviving cells after irradiation.
Int. J. Radiat. Biol. 53, 319-330 (1988)
The clonogenic potential of the progeny of irradiated cells was tested in vitro by replating irradiated cultures after various times, allowing between five and over 25 subsequent divisions to take place after irradiation. Whereas the plating efficiency of surviving Chinese hamster cells was not decreased, in C3H10T1/2 cells a dose-dependent but slight decrease in plating efficiency was observed even after the longest follow-up period. These data do not contradict the prevalent hypothesis in radiobiology that the proliferation potential of a colonogenic cell surviving after irradiation is not significantly different from that of a non-irradiated cell.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Zeitschrift
International Journal of Radiation Biology
Quellenangaben
Band: 53,
Heft: 2,
Seiten: 319-330
Verlag
Informa Healthcare
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Radiation Biology (ISB)