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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Inhibition of protein synthesis stimulates intracellular protein degradation in growing yeast cells.
Biochem. Biophys. Res. Commun. 72, 114-120 (1976)
In exponentially growing cells of Saccharomyces, cerevisiae, cycloheximide stimulated intracellular protein degradation to the same extent as did starvation for required amino acids. By using inhibitors of macromolecular synthesis and temperature-sensitive mutants defective in different steps of RNA and protein synthesis it could be demonstrated, that this stimulation of protein degradation was directly related to the inhibition of protein synthesis per se, but not connected to the cessation of ribosomal RNA synthesis or to the inhibition of cell growth.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0006-291X
e-ISSN
1090-2104
Quellenangaben
Band: 72,
Heft: 1,
Seiten: 114-120
Verlag
Elsevier
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Biochemie