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A clinical screening score for diabetic polyneuropathy: KORA F4 and AusDiab studies.
J. Diab. Complic. 29, 44-49 (2015)
AIMS: Since screening for distal sensorimotor polyneuropathy (DSPN) in individuals with diabetes is being underused, our aim was to develop a clinical screening score for identifying individuals with DSPN. METHODS: All participants with type 2 diabetes and aged 61-82 years from the German population-based KORA F4 Study (n=177) and the Australian population-based AusDiab Study (n=244) were combined into one study sample. Risk indicators of DSPN were identified and entered into a stepwise model-selection procedure, constructing two consecutive scores with increasing complexity (a base and clinical model). RESULTS: The prevalence of DSPN was 18.2% (95% confidence interval (CI): 14.7-22.3). The base model comprised age (years), height (cm), weight (kg), pain or discomfort in the feet and/or legs (yes/no), and duration of diabetes (years), yielding an area under the receiver operating characteristics curve (AUC) of 0.80 (95% CI: 0.76-0.85). The clinical model additionally included diastolic blood pressure (mmHg) and serum creatinine levels (mmol/l). The AUC increased only marginally to 0.82 (0.77-0.87) (p for AUC comparison=0.188). The internal validation of the scores produced similar AUCs. CONCLUSIONS: The screening scores developed in this study are a simple tool to differentiate between a high and low likelihood of having DSPN among individuals with type 2 diabetes.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
3.005
1.169
6
6
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Australia ; Diabetes Mellitus ; Distal Sensorimotor Polyneuropathy ; Epidemiology ; Germany ; Screening Score; Peripheral Neuropathy; Australian Population; Foot Complications; Risk; Care; Association; Prevalence; Threshold; Physician
Sprache
englisch
Veröffentlichungsjahr
2015
Prepublished im Jahr
2014
HGF-Berichtsjahr
2014
ISSN (print) / ISBN
1056-8727
e-ISSN
1056-8727
Zeitschrift
Journal of Diabetes and its Complications
Quellenangaben
Band: 29,
Heft: 1,
Seiten: 44-49
Verlag
Elsevier
Verlagsort
New York
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)
German Center for Diabetes Reseach (DZD)
German Center for Diabetes Reseach (DZD)
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-504000-006
G-504000-001
G-504090-001
G-504000-001
G-504090-001
PubMed ID
25457462
WOS ID
WOS:000348244400009
Scopus ID
84920545179
Erfassungsdatum
2014-12-04