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INFRAFRONTIER Consortium (de Castro, A. ; Fessele, S. ; Steinkamp, R. ; Hagn, M. ; Raess, M. ; Hrabě de Angelis, M. ; Meehan, T.F.*)

INFRAFRONTIER - providing mutant mouse resources as research tools for the international scientific community.

Nucleic Acids Res. 53, D1171-D1175 (2015)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
The laboratory mouse is a key model organism to investigate mechanism and therapeutics of human disease. The number of targeted genetic mouse models of disease is growing rapidly due to high-throughput production strategies employed by the International Mouse Phenotyping Consortium (IMPC) and the development of new, more efficient genome engineering techniques such as CRISPR based systems. We have previously described the European Mouse Mutant Archive (EMMA) resource and how this international infrastructure provides archiving and distribution worldwide for mutant mouse strains. EMMA has since evolved into INFRAFRONTIER (http://www.infrafrontier.eu), the pan-European research infrastructure for the systemic phenotyping, archiving and distribution of mouse disease models. Here we describe new features including improved search for mouse strains, support for new embryonic stem cell resources, access to training materials via a comprehensive knowledgebase and the promotion of innovative analytical and diagnostic techniques.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Mammalian Gene-function; Phenotyping Consortium; Mice; Access
ISSN (print) / ISBN 0305-1048
e-ISSN 1362-4962
Zeitschrift Nucleic Acids Research
Quellenangaben Band: 53, Heft: D1, Seiten: D1171-D1175 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Verlagsort Oxford
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Experimental Genetics (IEG)