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Eickholz, P.* ; Krigar, D.-M.* ; Kim, T.-S.* ; Reitmeir, P. ; Rawlinson, A.*

Stability of clinical and radiographic results after guided tissue regeneration in infrabony defects.

J. Periodontol. 78, 37-46 (2007)
DOI PMC
BACKGROUND: The aim of this 5-year follow-up study was to evaluate clinically and radiographically the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers. METHODS: Thirty-one patients with periodontitis and 50 infrabony defects that had been treated using GTR were recruited. Eleven defects were treated with non-resorbable expanded polytetrafluoroethylene membranes and 39 defects with bioabsorbable barriers. At baseline and 6 and 60 +/- 3 months after surgery, clinical parameters and standardized radiographs were obtained. During surgery and 60 +/- 3 months thereafter, the distance from the cemento-enamel junction to the base of the bony defect (vertical probing bone level [PBL-V]) was measured. Bone gain was evaluated using digital subtraction radiography. RESULTS: At 6 and 60 +/- 3 months after GTR, there was a statistically significant (P <0.001) reduction of probing depth (6 months: 4.31 +/- 1.76 mm; 60 months: 3.95 +/- 1.62 mm) and vertical clinical attachment level gains (CAL-V) (6 months: 3.34 +/- 1.66 mm; 60 months: 2.97 +/- 1.53 mm). From 6 to 60 months after GTR, three infrabony defects exhibited CAL-V loss >2 mm, and a small, statistically not significant mean CAL-V loss of 0.39 +/- 1.60 mm was observed. From baseline to 60 +/- 3 months, a significant PBL-V gain of 1.78 +/- 2.67 mm (P <0.001) and increase in bone density were observed (P = 0.003). CONCLUSION: The CAL-V gain achieved after GTR in infrabony defects using both non-resorbable and bioabsorbable barriers was stable after 5 years in 47 of 50 defects.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter clinical trials; defects/therapy; guided tissue regeneration; membranes; artificial; radiography; dental
ISSN (print) / ISBN 0022-3492
e-ISSN 1943-3670
Zeitschrift Journal of Periodontology
Quellenangaben Band: 78, Heft: 1, Seiten: 37-46 Artikelnummer: , Supplement: ,
Verlag American Academy of Periodontology
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Health Economics and Health Care Management (IGM)