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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Blood levels of polychlorinated biphenlys and organochlorinated pesticides in women from Istanbul, Turkey.
Environ. Monit. Assess. 187:132 (2015)
The human body is not a chemically uncontaminated system. Every simple action that humans undertake, such as drinking water, eating, nursing, and even breathing air, puts the system under environmental xenobiotic exposure stress. Environmental chemicals have been shown to produce unwanted effects on health and remove the right to healthy living, starting from the first encounter in utero to geriatrics, throughout the lifespan. Organochlorine pesticides (OCPs) and polychlorinated biphenyl (PCB) levels, important members of the persistent organic pollutants (POPs), have been detected before in human breast milk and also in the adipose tissue of women from different regions of Turkey; however, there was no information about the blood levels of these chemicals. This study generated the first information that evaluates OCP and PCB contamination levels in the blood of the women living in Turkey. The current study measured the blood concentrations of OCPs and PCBs in 58 healthy women (age 20-41 years; mean age 28 years) who were living in Istanbul, Turkey, in the years 2010-2012. Samples were analyzed for 29OCPs and 18 PCB congeners using high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS). PCB 153 was the predominant congener (643.2 pg/g lipid), followed by PCB 138 and PCB 180. 4,4'-DDE (24872.8 pg/g lipid) was the most common organochlorinated pesticide contaminant in studied blood samples. Results for analyzed chlorinated compounds were as follows: Sigma PCB 2682 +/- 3300 pg/g lipid; Sigma DDT 25,938+28,644 pg/g lipid; and Sigma HCH 2930 +/- 2222 pg/g lipid, respectively. The mean concentration of Sigma WHOPCB-TEQ was 0.037 pg/g on a lipid basis. This information will be important base data during the assessment of the general health concerns of women, as well as for studies about how endocrine disruptors affect humans for forthcoming studies.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Ocp ; Pcb ; Blood ; Women ; Turkey; Persistent Organic Pollutants; Northern European Countries; Human Breast-milk; Testicular Cancer; Endocrine Disruptors; Reproductive Health; Human Serum; Pcbs; Population; Exposure
ISSN (print) / ISBN
0167-6369
e-ISSN
1573-2959
Zeitschrift
Environmental Monitoring and Assessment
Quellenangaben
Band: 187,
Heft: 3,
Artikelnummer: 132
Verlag
Springer
Verlagsort
Dordrecht
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
PPM-MEX-Molecular EXposomics (MEX)