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Teles, P.* ; Barros, S.* ; Cardoso, S.* ; Facure, A.* ; da Rosa, L.A.R.* ; Santos, M.* ; Pereira, P.* ; Vaz, P.* ; Zankl, M.

A dosimetric study of prostate brachytherapy using Monte Carlo simulations with a voxel phantom, measurements and a comparison with a treatment planning procedure.

Radiat. Prot. Dosim. 165, 482-487 (2015)
Postprint DOI PMC
Open Access Green
In prostate brachytherapy treatments, there is an initial swelling of the prostate of the patient due to a prostate oedema related to the insertion of the seeds inside the prostate. The variation of the prostate volume can lead to variations in the final prescribed dose in treatment planning procedures. As such, it is important to understand their influence for dose optimisation purposes. This work reports on a dosimetric study of the swelling of the prostate in prostate brachytherapy using Monte Carlo simulations. Dosimetric measurements performed on a physical anthropomorphic tissue-equivalent prostate phantom and thermoluminescent dosimeters (TLDs) were used to validate the MC model. Finally the MC model was also used to simulate prostate swelling in a real treatment planning procedure. The obtained results indicate that the parameters mentioned above represent a source of uncertainty in dose assessment in prostate brachytherapy, and can be detrimental to a correct dose evaluation in treatment plannings, and that these parameters can be accurately determined by means of MC simulations with a voxel phantom.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Prostate brachytherapy; Monte Carlo simulation; prostate swelling; treatment planning; Brachytherapy; Cancer; I-125; Recommendations; Radiation
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Zeitschrift Radiation Protection Dosimetry
Quellenangaben Band: 165, Heft: 1-4, Seiten: 482-487 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Verlagsort Oxford
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Medicine (IRM)
Research Unit Medical Radiation Physics and Diagnostics (AMSD)