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Müller, T.D. ; Nogueiras, R.A.* ; Andermann, M.L.* ; Andrews, Z.B.* ; Anker, S.D.* ; Argente, J.* ; Batterham, R.* ; Benoit, S.C.* ; Bowers, C.Y.* ; Broglio, F.* ; Casanueva, F.F.F.* ; D'Alessio, D.* ; Depoortere, I.* ; Geliebter, A.A.* ; Ghigo, E.* ; Cole, P.A.* ; Cowley, M.A.* ; Cummings, D.E.* ; Dagher, A.* ; Diano, S.* ; Dickson, S.L.* ; Dieguez, C.* ; Granata, R.* ; Grill, H.J.* ; Grove, K.L.* ; Habegger, K.M.* ; Heppner, K.M.* ; Heiman, M.L.* ; Holsen, L.* ; Holst, B.* ; Inui, A.* ; Jansson, J.O.* ; Kirchner, H.* ; Korbonits, M.* ; Laferrère, B.* ; LeRoux, C.W.* ; López, M.D.* ; Morin, S. ; Nakazato, M.* ; Nass, R.* ; Perez-Tilve, D.* ; Pfluger, P.T. ; Schwartz, T.W.* ; Seeley, R.J.* ; Sleeman, M.W.* ; Sun, Y.* ; Sussel, L.* ; Tong, J.* ; Thorner, M.O.* ; van der Lely, A.J.* ; van der Ploeg, L.H.T.* ; Zigman, J.M.* ; Kojima, M.* ; Kangawa, K.* ; Smith, R.G.* ; Horvath, T.* ; Tschöp, M.H.

Ghrelin.

Mol. Metab. 4, 437–460 (2015)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Background: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. Scope of review: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. Major conclusions: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Ghrelin ; Growth Hormone Segretagogue Receptor
ISSN (print) / ISBN 2212-8778
e-ISSN 2212-8778
Zeitschrift Molecular Metabolism
Quellenangaben Band: 4, Heft: 6, Seiten: 437–460 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort Amsterdam
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes and Obesity (IDO)