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ß2-adrenoreceptor polymorphisms and asthma.
Lancet 368, 710-711 (2006)
A database comparison of the aminoacid sequence of the β2-adrenergic receptor from different species predicts in seconds that both the Arg16Gly and Gln27Glu variants are phenotypically benign.1 By contrast, the within-species analysis of the Homo sapiens gene took many years. With the first description in 1993 of all genetic variations of the β2 receptor,2 this receptor immediately became a prime target in many asthma studies.3,4 So why is the current study of Ian Hall and colleagues5 in today's Lancet important?
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0140-6736
e-ISSN
0099-5355
Zeitschrift
Lancet, The
Quellenangaben
Band: 368,
Heft: 9537,
Seiten: 710-711
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)