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Epidemiology of air pollution and diabetes.
Trends Endocrinol. Metab. 26, 384-394 (2015)
Air pollution affects a large proportion of the global population. Air pollutants are hypothesized to exert their effects via impaired endothelial function, elevated systemic inflammation, mitochondrial dysfunction, and oxidative stress, all of which are hallmarks of type 2 diabetes (T2D). Here we review epidemiological studies aimed at answering whether diabetes patients are more vulnerable to ambient (outdoor) air pollution exposure and whether air pollution is associated with diabetes development or other predisposing conditions for T2D. Current evidence suggests an association between air pollution exposure and T2D, but more critical analysis is warranted. Understanding the associations between air pollution exposure and the development of T2D is critical in our efforts to control sources of air pollution and their impact on the disease.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Air Pollution ; Gestational Diabetes ; Mortality ; Type 2 Diabetes; Long-term Exposure; Fine Particulate Matter; Case-crossover Analysis; Insulin-resistance; Daily Mortality; Risk-factors; Cardiovascular-disease; Susceptibility Factors; Effect Modifiers; Lung-cancer
ISSN (print) / ISBN
1043-2760
e-ISSN
1879-3061
Zeitschrift
Trends in Endocrinology and Metabolism
Quellenangaben
Band: 26,
Heft: 7,
Seiten: 384-394
Verlag
Elsevier
Verlagsort
London
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)