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Pretzl, B.* ; Kim, T.S.* ; Holle, H. ; Eickholz, P.*

Long-term results of guided tissue regeneration therapy with non-resorbable and bioabsorbable barriers. IV. A case series of infrabony defects after 10 years.

J. Periodontol. 79, 1491-1499 (2008)
DOI
BACKGROUND: A 10-year follow-up study was conducted to clinically evaluate the long-term results after guided tissue regeneration (GTR) therapy of infrabony defects using non-resorbable and bioabsorbable barriers. METHODS: Twelve pairs of contralateral infrabony defects were treated in 12 subjects with advanced periodontitis. Within each subject, one defect received a non-resorbable barrier and the other received a bioabsorbable barrier by random assignment. Clinical parameters were obtained at baseline and at 12 and 120+/-6 months after surgery. RESULTS: Eight of 12 subjects were available for the examination at 120+/-6 months. Twelve and 120+/-6 months after GTR therapy statistically significant (P<0.05) vertical clinical attachment level (CAL-V) gain was observed in both groups (3.4+/-1.0 mm and 1.5+/-1.2 mm for the control group at 12 and 120 months, respectively, and 3.3+/-1.6 mm and 3.5+/-2.5 mm for the test group at 12 and 120 months, respectively). However, 120+/-6 months after GTR therapy, three infrabony defects (two controls and one test) had lost >2 mm of the attachment that had been gained 12 months after GTR therapy, and a statistically significant mean CAL-V loss of 1.7+/-1.3 mm was observed from 12 to 120+/-6 months in the control group. One tooth in the control group was lost between 60 and 120+/-6 months. The case series failed to show statistically significant differences between test and control regarding CAL-V gain 120+/-6 months after surgery. CONCLUSION: CAL-V gain achieved 12 months after GTR therapy in infrabony defects using non-resorbable and bioabsorbable barriers was stable after 10 years in 12 of 16 defects.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter case series; guided tissue regeneration; periodontal; membranes; artificial; polyglactin 910/therapeutic use; polytetrafluoroethylene/therpaeutic use; randomized controled trial
ISSN (print) / ISBN 0022-3492
e-ISSN 1943-3670
Zeitschrift Journal of Periodontology
Quellenangaben Band: 79, Heft: 8, Seiten: 1491-1499 Artikelnummer: , Supplement: ,
Verlag American Academy of Periodontology
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Health Economics and Health Care Management (IGM)