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Determination and analysis of cellular metabolic changes by noncanonical Hedgehog signaling.
Methods Mol. Biol. 1322, 187-198 (2015)
Hedgehog is a morphogen essential for body patterning and proper embryonic development from flies to humans. Thought quiescent in adults, its inappropriate reactivation is associated with many disparate genetic and sporadic types of human cancers. Recent findings have demonstrated a key, yet unexpected, role of the Hedgehog signaling pathway in metabolic control. Here, we describe a panel of methods to determine and analyze cellular and organismal metabolic changes downstream of the Hedgehog signaling pathway.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Herausgeber
Riobo, N.A.*
Schlagwörter
Hedgehog; Metabolism; Glucose uptake; Calcium; Ampk
ISSN (print) / ISBN
1064-3745
e-ISSN
1940-6029
Konferenztitel
Hedgehog Signaling Protocols
Zeitschrift
Methods in Molecular Biology
Quellenangaben
Band: 1322,
Seiten: 187-198
Verlag
Springer
Verlagsort
Berlin [u.a.]
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Experimental Genetics (IEG)