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Taeger, D.* ; Pesch, B.* ; Kendzia, B.* ; Behrens, T.* ; Jöckel, K.-H.* ; Dahmann, D.* ; Siemiatycki, J.* ; Kromhout, H.* ; Vermeulen, R.* ; Peters, S.* ; Olsson, A.* ; Brüske, I. ; Wichmann, H.-E. ; Stücker, I.* ; Guida, F.* ; Tardón, A.* ; Merletti, F.* ; Mirabelli, D.* ; Richiardi, L.* ; Pohlabeln, H.* ; Ahrens, W.* ; Landi, M.T.* ; Caporaso, N.* ; Pesatori, A.C.* ; Mukeriya, A.* ; Szeszenia-Dabrowska, N.* ; Lissowska, J.* ; Gustavsson, P.* ; Field, J.* ; Marcus, M.W.* ; Fabianova, E.* ; 't Mannetje, A.* ; Pearce, N.* ; Rudnai, P.* ; Bencko, V.* ; Janout, V.* ; Dumitru, R.S.* ; Foretova, L.* ; Forastiere, F.* ; McLaughlin, J.* ; Demers, P.D.* ; Bueno-de-Mesquita, H.B.* ; Schüz, J.* ; Straif, K.* ; Brüning, T*

Lung cancer among coal miners, ore miners and quarrymen: Smoking-adjusted risk estimates from the synergy pooled analysis of case-control studies.

Scand. J. Work Environ. Health 41, 467-477 (2015)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
OBJECTIVES: Working in mines and quarries has been associated with an elevated lung cancer risk but with inconsistent results for coal miners. This study aimed to estimate the smoking-adjusted lung cancer risk among coal miners and compare the risk pattern with lung cancer risks among ore miners and quarrymen. METHODS: We estimated lung cancer risks of coal and ore miners and quarrymen among 14 251 lung cancer cases and 17 267 controls from the SYNERGY pooled case-control study, controlling for smoking and employment in other at-risk occupations. RESULTS: Ever working as miner or quarryman (690 cases, 436 controls) was associated with an elevated odds ratio (OR) of 1.55 [95% confidence interval (95% CI) 1.34-1.79] for lung cancer. Ore miners (53 cases, 24 controls) had a higher OR (2.34, 95% CI 1.36-4.03) than quarrymen (67 cases, 39 controls; OR 1.92, 95% CI 1.21-3.05) and coal miners (442 cases, 297 controls; OR 1.40, 95% CI 1.18-1.67), but CI overlapped. We did not observe trends by duration of exposure or time since last exposure. CONCLUSIONS: This pooled analysis of population-based studies demonstrated an excess lung cancer risk among miners and quarrymen that remained increased after adjustment for detailed smoking history and working in other at-risk occupations. The increase in risk among coal miners were less pronounced than for ore miners or quarrymen.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Coal Mining ; Histological Subtype ; Mining ; Ore Mining ; Population-based Study
ISSN (print) / ISBN 0355-3140
e-ISSN 1795-990X
Zeitschrift Scandinavian Journal of Work, Environment & Health
Quellenangaben Band: 41, Heft: 5, Seiten: 467-477 Artikelnummer: , Supplement: ,
Verlag Nordic Association of Occupational Safety and Health (NOROSH)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
Institute of Epidemiology II (EPI2)