PuSH - Publikationsserver des Helmholtz Zentrums München

Razansky, D.

Optoacoustic imaging.

In: Comprehensive Biomedical Physics. Vol. 4: Optical Molecular Imaging. 2014. 281-300
DOI
Optoacoustic imaging is emerging as a powerful modality for in vivo imaging of small animals and humans that can simultaneously provide anatomical, functional, and molecular contrast, overcoming a variety of long-standing limitations imposed by light scattering in deep tissues. Due to its hybrid nature, that is, optical excitation and ultrasonic detection, the method benefits from both the rich and versatile optical contrast and high (diffraction-limited) spatial resolution associated with the low scattering nature of ultrasonic wave propagation. By detecting tiny sound vibrations, resulting from selective absorption of light at multiple wavelengths, multispectral optoacoustic tomography can now 'hear color' in three dimensions, that is, deliver volumetric spectrally enriched (color) images from deep living tissues at high spatial resolution and in real time. These newfound imaging abilities directly relate to preclinical screening applications in animal models and are foreseen to significantly impact clinical decision making as well. This article provides the technical essentials of imaging with optoacoustics, contrast enhancement approaches, and discusses its prospective applications in biology and medicine.
Altmetric
Weitere Metriken?
[➜Einloggen]
Zusatzinfos bearbeiten [➜Einloggen]
Publikationstyp Artikel: Sammelbandbeitrag/Buchkapitel
Herausgeber Brahme, A.*
Korrespondenzautor
Schlagwörter Biomedical Imaging ; Microscopy ; Optoacoustic Tomography ; Photoacoustics
ISBN 978-0-444-53633-4
Bandtitel Comprehensive Biomedical Physics. Vol. 4: Optical Molecular Imaging
Quellenangaben Band: , Heft: , Seiten: 281-300 Artikelnummer: , Supplement: ,
Nichtpatentliteratur Publikationen
Institut(e) Institute of Biological and Medical Imaging (IBMI)