PuSH - Publikationsserver des Helmholtz Zentrums München: Performance of a Multispectral Optoacoustic Tomography (MSOT) system equipped with 2D vs. 3D handheld probes for potential clinical translation.

Informationen

Hinweise zu Qualitätskriterien von Zeitschriften

Open-Access-Richtlinie der Helmholtz-Gemeinschaft 2016

CC Licencences

Metriken für Publikationen

Navigation

Startseite

English

Recherche

Erweiterte Suche

Durchblättern nach ...

... HMGU-Autoren/Konsortien

... Organisationsstruktur

... Zeitschriften

... Publikationstypen

... Forschungsdaten

... Arbeitsgruppen

... Erscheinungsjahr

Publikationen im Überblick

Statistik

HGF Fortschrittsbericht

OA Publikationen

Eintragen

Neue Publikation eintragen

Neue Publikation holen aus...

...EVA

Fehlende Publikation melden

Highlights

Suche

Hilfe & Kontakt

Ansprechpartner

Hilfe

Datenschutz

Helmholtz Open Science

Bibliometrische Indikatoren

SHERPA/RoMEO

DOAJ

Export:

Text

Endnote (RIS) BIB

BibTeX

Neuschmelting, V.* ; Burton, N.C.* ; Lockau, H.* ; Urich, A.* ; Harmsen, S.* ; Ntziachristos, V. ; Kircher, M.F.*

Performance of a Multispectral Optoacoustic Tomography (MSOT) system equipped with 2D vs. 3D handheld probes for potential clinical translation.

Photoacoustics 4, 1-10 (2016)

Verlagsversion

Anhang

DOI

PMC

	Open Access Gold

Abstract
Metriken
Zusatzinfos

A handheld approach to optoacoustic imaging is essential for the clinical translation. The first 2- and 3-dimensional handheld multispectral optoacoustic tomography (MSOT) probes featuring real-time unmixing have recently been developed. Imaging performance of both probes was determined in vitro and in a brain melanoma metastasis mouse model in vivo. T1-weighted MR images were acquired for anatomical reference. The limit of detection of melanoma cells in vitro was significantly lower using the 2D than the 3D probe. The signal decrease was more profound in relation to depth with the 3D versus the 2D probe. Both approaches were capable of imaging the melanoma tumors qualitatively at all time points. Quantitatively, the 2D approach enabled closer anatomical resemblance of the tumor compared to the 3D probe, particularly at depths beyond 3 mm. The 3D probe was shown to be superior for rapid 3D imaging and, thus, holds promise for more superficial target structures.

Impact Factor

Scopus SNIP

Scopus
Cited By

Altmetric

4.930

1.781