PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Koch, M. ; Ntziachristos, V.

Advancing surgical vision with fluorescence imaging.

Annu. Rev. Med. 67, 153-164 (2016)
Verlagsversion DOI
Open Access Gold
Surgical success depends on the accuracy with which disease and vital tissue can be intraoperatively detected. However, the dominant visualization approach, i.e., human vision, does not see under the tissue surface and operates on low contrast between sites of disease, such as cancer, and the surrounding tissue. Intraoperative fluorescence imaging is emerging as a highly effective method to improve surgical vision and offers the potential to be intergrated seamlessly into the normal workflow of the operating room without causing disruption or undue delay. We review and compare two critical fluorescence imaging directions: one that uses nonspecific fluorescence dyes, addressing tissue perfusion and viability, and one that uses targeted agents, interrogating pathophysiological features of disease. These two approaches present detection sensitivity challenges that may differ by orders of magnitude and require different detection strategies. Nevertheless, fluorescence imaging provides the surgeon with previously unavailable real-time feedback that improves surgical precision and can become essential for interventional decision-making.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
10.954
3.390
62
68
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Fluorescence Agents ; Intraoperative Imaging ; Molecular Imaging ; Sentinel Lymph Node Mapping ; Targeted Fluorescence Imaging
Sprache englisch
Veröffentlichungsjahr 2016
HGF-Berichtsjahr 2016
ISSN (print) / ISBN 0066-4219
e-ISSN 1545-326X
Zeitschrift Annual Review of Medicine
Quellenangaben Band: 67, Heft: , Seiten: 153-164 Artikelnummer: , Supplement: ,
Verlag Annual Reviews
Verlagsort Palo Alto, Calif. [u.a.]
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-505500-001
DOI 10.1146/annurev-med-051914-022043
WOS ID WOS:000368346100011
Scopus ID 84954510767
Erfassungsdatum 2016-01-28
[➜Korrektur melden]