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Ishiuchi, T.* ; Torres-Padilla, M.E.*

LINEing germ and embryonic stem cells' silencing of retrotransposons.

Genes Dev. 28, 1381-1383 (2014)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, one type of non-long terminal repeat (LTR) retrotransposon, long interspersed nuclear element 1 (LINE1), is capable of retrotransposition. Two studies in this issue, Pezic and colleagues (pp. 1410-1428) and Castro-Diaz and colleagues (pp. 1397-1409), provide novel insight into the regulation of LINE1s in human embryonic stem cells and mouse germ cells and shed new light on the conservation of complex mechanisms to ensure silencing of transposable elements in mammals.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Dna Methylation ; Kap1 ; Line1 ; Evolution ; Pirna ; Transposon
ISSN (print) / ISBN 0890-9369
e-ISSN 1549-5477
Zeitschrift Genes and Development
Quellenangaben Band: 28, Heft: 13, Seiten: 1381-1383 Artikelnummer: , Supplement: ,
Verlag Cold Spring Harbor Laboratory Press
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed