PuSH - Publikationsserver des Helmholtz Zentrums München

Restrictions in time and space - new insights into generation of specific neuronal subtypes in the adult mammalian brain.

Eur. J. Neurosci. 33, 1045-1054 (2011)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Key questions in regard to neuronal repair strategies are which cells are best suited to regenerate specific neuronal subtypes and how much of a neuronal circuit needs to persist in order to allow its functional repair. Here we discuss recent findings in the field of adult neurogenesis, which shed new light on these questions. Neural stem cells in the adult brain generate very distinct types of neurons depending on their regional and temporal specification. Moreover, distinct brain regions differ in the mode of neuron addition in adult neurogenesis, suggesting that different brain circuits may be able to cope differently with the incorporation of new neurons. These new insights are then considered in regard to the choice of cells with the appropriate region-specific identity for repair strategies.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
3.658
1.004
21
29
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter neural stem cells; neurogenesis; neuronal repair; neuronal subtype specification; olfactory bulk; transcription factors
Sprache englisch
Veröffentlichungsjahr 2011
HGF-Berichtsjahr 2011
ISSN (print) / ISBN 0953-816X
e-ISSN 1460-9568
Quellenangaben Band: 33, Heft: 6, Seiten: 1045-1054 Artikelnummer: , Supplement: ,
Verlag Wiley
Begutachtungsstatus Peer reviewed
POF Topic(s) 30204 - Cell Programming and Repair
Forschungsfeld(er) Stem Cell and Neuroscience
PSP-Element(e) G-500800-001
PubMed ID 21395847
Scopus ID 79952583391
Erfassungsdatum 2011-07-19